A New Jersey native of Cuban descent, Fumero's parents moved to the United States from Cuba as teenagers. Fumero received a Bachelor of Fine Arts in Drama from New York University in December 2003.
On November 16, 2015, she announced via social media that she was pregnant with her first child, her pregnancy was not written in to the show. She welcomed a baby boy named Enzo on March 24, 2016, the same day the show was renewed for a fourth season.
The second actress to portray Adriana on One Life to Live, Fumero joined the series on January 20, 2004. Adriana is the long-lost daughter of longtime character Dorian Cramer Lord, portrayed byDaytime Emmy-winner Robin Strasser on-and-off since 1979. Fumero won the role of Adriana on her last day as a student at NYU. In late 2007 she decided not to renew her contract with the series, but remained on a recurring status to wrap up Adriana's storyline. Fumero's last appearance was June 11, 2008. Fumero returned to One Life to Live in September 2008 for a 15-episode run. Fumero returned on OLTL on February 12, 2010 for a guest stint to help usher in the return of Kelly Cramer (Gina Tognoni).
Fumero made her big screen debut as the lead in the 2008 independent film, Tiny Dancer.
In 2010, Fumero played Zoe (aka Headband Girl) in 4 episodes on Gossip Girl. The episodes are: "The Empire Stricks Jack", "It's a Dad, Dad, Dad, Dad World" (Season 3) and "The Undergraduates" and "Goodbye, Columbia" (Season 4).
- 2004 - 2008; 2010; 2011: One Life to Live as Adriana Cramer (Role: January 22, 2004 - June 11, 2008; September 18 - October 28, 2008; February 12 - March 2, 2010; November 9 & November 10, 2010; January 25, 2011)
- 2005: All My Children as Adriana Cramer (2 episodes)
- 2007: Descent as Dorm Girl #2 Descent (uncredited)
- 2009: I Hope They Serve Beer in Hell as Melissa
- 2009: Haute & Bothered as Jo (2 episodes)
- 2009: Important Things with Demetri Martin as April (1 episode)
- 2009: Tiny Dancer as Ati (as Melissa Gallo)
- 2010: The Mentalist as Carmen Soledad (1 episode)
- 2010 -: Gossip Girl as Zoe (aka Headband Girl)
- 2012: CSI: New York as Michelle Rhodes
- She shares a birthday (August 19) with Kyra Sedgewick.
- ^ a b Soap Opera Digest, Vol. 33, No. 1, January 1, 2008, page 5. "Gallo will now go by Melissa Fumero" following her December 9, 2007 marriage to OLTL costar David Fumero.
- ^ a b c d e f Melissa Fumero bio - ABC .com
- ^ a b "SOAP STAR STATS: Melissa Fumero (Adriana, OLTL)". SoapOperaDigest.com. Retrieved May 12, 2009.
- ^ One Life to Live recap (6/11/08) - ABC.com
- ^ Mistretta, Amy (September 16, 2008). "Melissa Fumero Confirms Her OLTL Return To Soaps.com!". Soaps.com. Retrieved May 12, 2009.